Rare Causes of Anisocoria: Ipratropium bromide and Angel’s trumpet

Anisocoria with high dose ipratropium bromide inhaler.

I bromide is an atropine derived anti-cholinergic bronchodilator used in obstructive lung diseases. Anisocoria mainly caused by the direct effect of nebulized ipratropium bromide via a leaking mask has been well described in the literature.1,2 However, anisocoria induced by systemic absorption after long-term use of high dose ipratropium inhaler is not well reported. We report a case of a 24-ye...

Transient anisocoria in a patient treated with nebulized ipratropium bromide

Purpose We present a case report of a 44-year old female patient with complicated pneumonia who developed anisocoria after treatment with inhaled ipratropium bromide. Discontinuation of ipratropium bromide treatment led to complete resolution of anisocoria. Observation A 44-year old female patient was admitted to the Department of Pulmonology due to high body temperature (40.0 °C), coughing a...

Ipratropium-bromide-induced acute anisocoria in the intensive care setting due to ill-fitting face masks.

Anisocoria, or unequal pupil size, may be an early sign of an impending neurologic emergency in any patient.1 Acute unilateral mydriasis is often suggestive of a lifethreatening condition affecting cranial nerve function, such as tumor compression, intracranial hypertension with impending uncal herniation, expanding intracranial aneurysm, or hemorrhage. Benign mydriasis can be due to prior trau...

Ipratropium bromide bronchodilator solution.

Effects of Inhaled Albuterol and Ipratropium Bromide

Study objective: Systemic administration of P-agonist and anticholinergic drugs markedly impair normal autonomic heart rate control. The purpose of this study was to quantify and compare the effects of therapeutic doses of inhaled albuterol and ipratropium on autonomic control of the cardiovascular system. Design: Randomized, double-blind, placebo-controlled, crossover design study. Setting: Te...